Human NPAS3 activation kit by CRISPRa

SKU GA111954

NPAS3 CRISPRa kit - CRISPR gene activation of human neuronal PAS domain protein 3

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: NPAS3
• Locus ID: 64067
• Components:

  GA111954G1, NPAS3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA111954G2, NPAS3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA111954G3, NPAS3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001164749, NM_001165893, NM_022123, NM_173159
• UniProt ID: Q8IXF0
• Synonyms: bHLHe12; MOP6; PASD6
• Summary: This gene encodes a member of the basic helix-loop-helix and PAS domain-containing family of transcription factors. The encoded protein is localized to the nucleus and may regulate genes involved in neurogenesis. Chromosomal abnormalities that affect the coding potential of this gene are associated with schizophrenia and cognitive disability. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]