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Human SAV1 activation kit by CRISPRa

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SKU
GA111853
SAV1 CRISPRa kit - CRISPR gene activation of human salvador family WW domain containing protein 1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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$447.00
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Other products for "SAV1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol SAV1
Locus ID 60485
Components

GA111853G1, SAV1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA111853G2, SAV1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA111853G3, SAV1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_021818
UniProt ID Q9H4B6
Synonyms SAV; WW45; WWP4
Summary WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein with two WW domains, a SARAH domain, and a coiled-coil region and is ubiquitously expressed in adult tissues. This protein binds to MST1 (mammalian sterile 20-like kinase 1) and promotes MST1-induced apoptosis. It has also been shown to bind to HAX1 (hematopoietic cell-specific protein 1 (HS1)-associated protein X-1) and to attenuate the anti-apoptotic effects of HAX1. Studies in human and mouse suggest this gene acts as a tumor suppressor. provided by RefSeq, Aug 2012
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Other Versions
SKU Description Size Price
KN404389 SAV1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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