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Human DENND1A activation kit by CRISPRa

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SKU
GA111700
DENND1A CRISPRa kit - CRISPR gene activation of human DENN domain containing 1A
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC207881 DENND1A (Myc-DDK-tagged)-Human DENN/MADD domain containing 1A (DENND1A), transcript variant 2
10 ug
$520.00

Other products for "DENND1A"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol DENND1A
Locus ID 57706
Components

GA111700G1, DENND1A gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA111700G2, DENND1A gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA111700G3, DENND1A gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_020946, NM_024820, NM_001352964, NM_001352965, NM_001352966, NM_001352967, NM_001352968, NR_148208
UniProt ID Q8TEH3
Synonyms FAM31A; KIAA1608
Summary Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1A, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2; see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson, 2010 PubMed 20154091).supplied by OMIM, Nov 2010
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Documents
Resources
Other Versions
SKU Description Size Price
KN407881 DENND1A - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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