Human FNIP2 activation kit by CRISPRa

SKU
GA111624
FNIP2 CRISPRa kit - CRISPR gene activation of human folliculin interacting protein 2
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol FNIP2
Locus ID 57600
Components

GA111624G1, FNIP2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA111624G2, FNIP2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA111624G3, FNIP2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001323916, NM_001346043, NM_020840, NM_001366843
UniProt ID Q9P278
Synonyms FNIPL; MAPO1
Summary This gene encodes a protein that binds to the tumor suppressor folliculin and to AMP-activated protein kinase (AMPK), and may play a role cellular metabolism and nutrient sensing by regulating the AMPK-mechanistic target of rapamycin signaling pathway. The encoded protein may also be involved in regulating the O6-methylguanine-induced apoptosis signaling pathway. This gene has a closely related paralog that encodes a protein with similar binding activities. Both related proteins also associate with the molecular chaperone heat shock protein-90 (Hsp90) and negatively regulate its ATPase activity and facilitate its association with folliculin. provided by RefSeq, Jul 2017
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Documents
Resources
Other Versions
SKU Description Size Price
KN419509 FNIP2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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