Human SPHK2 activation kit by CRISPRa

SKU
GA111232
SPHK2 CRISPRa kit - CRISPR gene activation of human sphingosine kinase 2
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol SPHK2
Locus ID 56848
Components

GA111232G1, SPHK2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA111232G2, SPHK2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA111232G3, SPHK2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001204158, NM_001204159, NM_001204160, NM_001243876, NM_020126
UniProt ID Q9NRA0
Synonyms SK-2; SK 2; SPK-2; SPK 2
Summary This gene encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. provided by RefSeq, Aug 2011
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Other Versions
SKU Description Size Price
KN403019 SPHK2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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