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Human TIP120A (CAND1) activation kit by CRISPRa

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SKU
GA111005
CAND1 CRISPRa kit - CRISPR gene activation of human cullin associated and neddylation dissociated 1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CAND1
Locus ID 55832
Components

GA111005G1, TIP120A gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA111005G2, TIP120A gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA111005G3, TIP120A gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_018448, NM_001329674, NM_001329675, NM_001329676
UniProt ID Q86VP6
Synonyms TIP120; TIP120A
Summary This gene encodes an essential regulator of Cullin-RING ubiquitin ligases, which are in involved in ubiquitinylation of proteins degraded by the Ub proteasome system. The encoded protein binds to unneddylated cullin-RING box protein complexes and acts as an inhibitor of cullin neddylation and of Skp1, cullin, and F box ubiquitin ligase complex assembly and activity. In mammalian cell culture, this protein predominantly localizes to the cytoplasm. Knockdown of this gene in preadipocytes results in blocked adipogenesis. Alternative splicing results in multiple transcript variants. provided by RefSeq, Jul 2016
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Documents
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Other Versions
SKU Description Size Price
KN408212 CAND1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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