Human TRM1 (TRMT1) activation kit by CRISPRa

SKU
GA110830
TRMT1 CRISPRa kit - CRISPR gene activation of human tRNA methyltransferase 1
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol TRMT1
Locus ID 55621
Components

GA110830G1, TRM1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA110830G2, TRM1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA110830G3, TRM1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001136035, NM_001142554, NM_017722, NM_001351760, NM_001351761, NM_001351762
UniProt ID Q9NXH9
Synonyms TRM1
Summary This gene encodes a tRNA-modifying enzyme that acts as a dimethyltransferase, modifying a single guanine residue at position 26 of the tRNA. The encoded enzyme has both mono- and dimethylase activity when exogenously expressed, and uses S-adenosyl methionine as a methyl donor. The C-terminal region of the encoded protein has both a zinc finger motif, and an arginine/proline-rich region. Mutations in this gene have been implicated in autosomal recessive intellectual disorder (ARID). Alternative splicing results in multiple transcript variants encoding different isoforms. There is a pseudogene of this gene on the X chromosome. provided by RefSeq, May 2017
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Other Versions
SKU Description Size Price
KN408040 TRMT1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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