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Human LRDD (PIDD1) activation kit by CRISPRa

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SKU
GA110742
PIDD1 CRISPRa kit - CRISPR gene activation of human p53-induced death domain protein 1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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RC203713 PIDD (Myc-DDK-tagged)-Human p53-induced death domain protein (PIDD), transcript variant 3
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Other products for "PIDD1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PIDD1
Locus ID 55367
Components

GA110742G1, LRDD gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA110742G2, LRDD gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA110742G3, LRDD gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_018494, NM_145886, NM_145887
UniProt ID Q9HB75
Synonyms DKFZp434D229; leucine-rich and death domain containing; leucine-rich repeats and death domain containing; leucine rich repeat and death domain containing protein; MGC16925; PIDD
Summary The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD), and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis. Alternative splicing results in multiple transcript variants. provided by RefSeq, Aug 2010
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Documents
Resources
Other Versions
SKU Description Size Price
KN403713 PIDD1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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