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Human NUDT15 activation kit by CRISPRa

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SKU
GA110659
NUDT15 CRISPRa kit - CRISPR gene activation of human nudix hydrolase 15
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA811479 NUDT15 mouse monoclonal antibody,clone OTI4B9 100 ul
$447.00
RC210477 NUDT15 (Myc-DDK-tagged)-Human nudix (nucleoside diphosphate linked moiety X)-type motif 15 (NUDT15)
10 ug
$225.00

Other products for "NUDT15"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol NUDT15
Locus ID 55270
Components

GA110659G1, NUDT15 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA110659G2, NUDT15 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA110659G3, NUDT15 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001304745, NM_018283, NR_136687, NR_136688
UniProt ID Q9NV35
Synonyms MTH2
Summary This gene encodes an enzyme that belongs to the Nudix hydrolase superfamily. Members of this superfamily catalyze the hydrolysis of nucleoside diphosphates, including substrates like 8-oxo-dGTP, which are a result of oxidative damage, and can induce base mispairing during DNA replication, causing transversions. The encoded enzyme is a negative regulator of thiopurine activation and toxicity. Mutations in this gene result in poor metabolism of thiopurines, and are associated with thiopurine-induced early leukopenia. Multiple pseudogenes of this gene have been identified. provided by RefSeq, Apr 2016
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Documents
Resources
Other Versions
SKU Description Size Price
KN410477 NUDT15 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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