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Human FAM35A activation kit by CRISPRa

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SKU
GA110163
SHLD2 CRISPRa kit - CRISPR gene activation of human shieldin complex subunit 2
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA315529 Rabbit polyclonal anti-FAM35A/B antibody
100 ul
$380.00
RC208697 FAM35A (Myc-DDK-tagged)-Human family with sequence similarity 35, member A (FAM35A)
10 ug
$765.00

Other products for "SHLD2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol SHLD2
Locus ID 54537
Components

GA110163G1, FAM35A gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA110163G2, FAM35A gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA110163G3, FAM35A gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001330112, NM_019054
UniProt ID Q86V20
Synonyms bA163M19.1; FAM35A1
Summary Component of the shieldin complex, which plays an important role in repair of DNA double-stranded breaks (DSBs) (PubMed:29656893, PubMed:29789392). During G1 and S phase of the cell cycle, the complex functions downstream of TP53BP1 to promote non-homologous end joining (NHEJ) and suppress DNA end resection (PubMed:29656893, PubMed:29789392). Mediates various NHEJ-dependent processes including immunoglobulin class-switch recombination, and fusion of unprotected telomeres (PubMed:29656893).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN408697 FAM35A - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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