Human GNG13 activation kit by CRISPRa

SKU GA109983

GNG13 CRISPRa kit - CRISPR gene activation of human G protein subunit gamma 13

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: GNG13
• Locus ID: 51764
• Components:

  GA109983G1, GNG13 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA109983G2, GNG13 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA109983G3, GNG13 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_016541
• UniProt ID: Q9P2W3
• Synonyms: G(gamma)13; h2-35
• Summary: Heterotrimeric G proteins, which consist of alpha (see MIM 139320), beta (see MIM 139380), and gamma subunits, function as signal transducers for the 7-transmembrane-helix G protein-coupled receptors. GNG13 is a gamma subunit that is expressed in taste, retinal, and neuronal tissues and plays a key role in taste transduction (Li et al., 2006 [PubMed 16473877]).[supplied by OMIM, Oct 2009]