Human CCDC53 (WASHC3) activation kit by CRISPRa

SKU
GA109502
WASHC3 CRISPRa kit - CRISPR gene activation of human WASH complex subunit 3
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol WASHC3
Locus ID 51019
Components

GA109502G1, CCDC53 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA109502G2, CCDC53 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA109502G3, CCDC53 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001301107, NM_016053
UniProt ID Q9Y3C0
Synonyms CGI-116
Summary Acts at least in part as component of the WASH core complex whose assembly at the surface of endosomes seems to inhibit WASH nucleation-promoting factor (NPF) activity in recruiting and activating the Arp2/3 complex to induce actin polymerization, and which is involved in regulation of the fission of tubules that serve as transport intermediates during endosome sorting (PubMed:19922875, PubMed:20498093).UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
KN403045 CCDC53 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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