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Human COQ6 activation kit by CRISPRa

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SKU
GA109489
COQ6 CRISPRa kit - CRISPR gene activation of human coenzyme Q6, monooxygenase
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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100 ul
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RC204353 COQ6 (Myc-DDK-tagged)-Human coenzyme Q6 homolog, monooxygenase (S. cerevisiae) (COQ6), nuclear gene encoding mitochondrial protein, transcript variant 1
10 ug
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Other products for "COQ6"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol COQ6
Locus ID 51004
Components

GA109489G1, COQ6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA109489G2, COQ6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA109489G3, COQ6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_015940, NM_182476, NM_182480
UniProt ID Q9Y2Z9
Synonyms CGI-10; CGI10; COQ10D6
Summary The protein encoded by this gene belongs to the ubiH/COQ6 family. It is an evolutionarily conserved monooxygenase required for the biosynthesis of coenzyme Q10 (or ubiquinone), which is an essential component of the mitochondrial electron transport chain, and one of the most potent lipophilic antioxidants implicated in the protection of cell damage by reactive oxygen species. Knockdown of this gene in mouse and zebrafish results in decreased growth due to increased apoptosis. Mutations in this gene are associated with autosomal recessive coenzyme Q10 deficiency-6 (COQ10D6), which manifests as nephrotic syndrome with sensorineural deafness. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. provided by RefSeq, Jun 2012
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Other Versions
SKU Description Size Price
KN404353 COQ6 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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