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Human KCNK4 activation kit by CRISPRa

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SKU
GA109446
KCNK4 CRISPRa kit - CRISPR gene activation of human potassium two pore domain channel subfamily K member 4
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA328664 Rabbit Polyclonal Anti-K2P4.1 (TRAAK)
50 ul
$1,145.00
RC213846 KCNK4 (Myc-DDK-tagged)-Human potassium channel, subfamily K, member 4 (KCNK4)
10 ug
$457.00

Other products for "KCNK4"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol KCNK4
Locus ID 50801
Components

GA109446G1, KCNK4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA109446G2, KCNK4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA109446G3, KCNK4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001317090, NM_016611, NM_033310, NM_033311, NR_133660, NR_133661
UniProt ID Q9NYG8
Synonyms K2p4.1; K2P4.1 potassium channel; potassium channel, subfamily K, member 4; TRAAK; TRAAK, DKFZP566E164; TRAAK1; TWIK-related arachidonic acid-stimulated potassium channel protein; two pore K+ channel KT4.1
Summary This gene encodes a member of the TWIK-related arachidonic acid-stimulated two pore potassium channel subfamily. The encoded protein homodimerizes and functions as an outwardly rectifying channel. This channel is regulated by polyunsaturated fatty acids, temperature and mechanical deformation of the lipid membrane. This protein is expressed primarily in neural tissues and may be involved in regulating the noxious input threshold in dorsal root ganglia neurons. Alternate splicing results in multiple transcript variants. Naturally occurring read-through transcripts also exist between this gene and the downstream testis expressed 40 (TEX40) gene, as represented in GeneID: 106780802. provided by RefSeq, Nov 2015
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Documents
Resources
Other Versions
SKU Description Size Price
KN413846 KCNK4 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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