Human NOB1 activation kit by CRISPRa

SKU
GA109192
NOB1 CRISPRa kit - CRISPR gene activation of human NIN1 (RPN12) binding protein 1 homolog
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol NOB1
Locus ID 28987
Components

GA109192G1, NOB1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA109192G2, NOB1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA109192G3, NOB1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_014062, NR_074074
UniProt ID Q9ULX3
Synonyms ART-4; MST158; MSTP158; NOB1P; PSMD8BP1
Summary In yeast, over 200 protein and RNA cofactors are required for ribosome assembly, and these are generally conserved in eukaryotes. These factors orchestrate modification and cleavage of the initial 35S precursor rRNA transcript into the mature 18S, 5.8S, and 25S rRNAs, folding of the rRNA, and binding of ribosomal proteins and 5S RNA. Nob1 is involved in pre-rRNA processing. In a late cytoplasmic processing step, Nob1 cleaves a 20S rRNA intermediate at cleavage site D to produce the mature 18S rRNA (Lamanna and Karbstein, 2009 PubMed 19706509).supplied by OMIM, Nov 2010
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Documents
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Other Versions
SKU Description Size Price
KN409537 NOB1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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