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Human LAT activation kit by CRISPRa

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SKU
GA108981
LAT CRISPRa kit - CRISPR gene activation of human linker for activation of T cells
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC204180 LAT (Myc-DDK-tagged)-Human linker for activation of T cells (LAT), transcript variant 2
10 ug
$450.00

Other products for "LAT"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol LAT
Locus ID 27040
Components

GA108981G1, LAT gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA108981G2, LAT gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA108981G3, LAT gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001014987, NM_001014988, NM_001014989, NM_014387
UniProt ID O43561
Synonyms LAT1; pp36
Summary The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Jul 2008
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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