Human FGF22 activation kit by CRISPRa

SKU GA108963

FGF22 CRISPRa kit - CRISPR gene activation of human fibroblast growth factor 22

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: FGF22
• Locus ID: 27006
• Components:

  GA108963G1, FGF22 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA108963G2, FGF22 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA108963G3, FGF22 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001300812, NM_020637
• UniProt ID: Q9HCT0
• Summary: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The mouse homolog of this gene was found to be preferentially expressed in the inner root sheath of the hair follicle, which suggested a role in hair development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]