Human RPS6KC1 activation kit by CRISPRa

SKU GA108940

RPS6KC1 CRISPRa kit - CRISPR gene activation of human ribosomal protein S6 kinase C1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: RPS6KC1
• Locus ID: 26750
• Components:

  GA108940G1, RPS6KC1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA108940G2, RPS6KC1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA108940G3, RPS6KC1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001136138, NM_001287218, NM_001287219, NM_001287220, NM_001287221, NM_012424, NM_058253, NM_001349646, NM_001349647, NM_001349648, NM_001349649, NM_001349650, NM_001349651, NM_001349652, NM_001349653, NM_001349654, NM_001349657, NM_001349658, NM_001349659, NM_001349660, NM_001349661, NM_001349662, NM_001349663, NM_001349664, NM_001349665, NM_001349666, NM_001349667, NM_001349668, NM_001349669, NM_001349670, NM_001349671, NM_001349672, NR_146207, NR_146208, NR_146209, NR_146210
• UniProt ID: Q96S38
• Synonyms: humS6PKh1; RPK118; RSKL1; S6K-delta-1; S6PKh1
• Summary: Sphingosine kinase catalyzes the formation of sphingosine 1 phosphate, a lipid cellular messenger. The protein encoded by this gene can bind to sphingosine kinase and to phosphatidylinositol 3-phosphate, suggesting a role in sphingosine 1 phophate signaling. The encoded protein can also bind to peroxiredoxin-3 and may help transport it to mitochondria. [provided by RefSeq, Mar 2017]