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Human PTPN18 activation kit by CRISPRa

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SKU
GA108864
PTPN18 CRISPRa kit - CRISPR gene activation of human protein tyrosine phosphatase non-receptor type 18
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC226517 PTPN18 (Myc-DDK-tagged)-Human protein tyrosine phosphatase, non-receptor type 18 (brain-derived) (PTPN18), transcript variant 2
10 ug
$457.00

Other products for "PTPN18"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PTPN18
Locus ID 26469
Components

GA108864G1, PTPN18 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA108864G2, PTPN18 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA108864G3, PTPN18 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001142370, NM_014369
UniProt ID Q99952
Synonyms BDP1; PTP-HSCF
Summary The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, the mitotic cycle, and oncogenic transformation. This PTP contains a PEST motif, which often serves as a protein-protein interaction domain, and may be related to protein intracellular half-live. This protein can differentially dephosphorylate autophosphorylated tyrosine kinases that are overexpressed in tumor tissues, and it appears to regulate HER2, a member of the epidermal growth factor receptor family of receptor tyrosine kinases. Two transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Nov 2008
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Documents
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Other Versions
SKU Description Size Price
KN413476 PTPN18 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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