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Human HECTD1 activation kit by CRISPRa

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SKU
GA108570
HECTD1 CRISPRa kit - CRISPR gene activation of human HECT domain E3 ubiquitin protein ligase 1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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RC221760 HECTD1 (Myc-DDK-tagged)-Human HECT domain containing 1 (HECTD1)
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Other products for "HECTD1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol HECTD1
Locus ID 25831
Components

GA108570G1, HECTD1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA108570G2, HECTD1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA108570G3, HECTD1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_015382
UniProt ID Q9ULT8
Synonyms EULIR
Summary E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates 'Lys-63'-linked polyubiquitination of HSP90AA1 which leads to its intracellular localization and reduced secretion. Negatively regulating HSP90AA1 secretion in cranial mesenchyme cells may impair their emigration and may be essential for the correct development of the cranial neural folds and neural tube closure.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN421760 HECTD1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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