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Human PATZ1 activation kit by CRISPRa

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SKU
GA108426
PATZ1 CRISPRa kit - CRISPR gene activation of human POZ/BTB and AT hook containing zinc finger 1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA809258 PATZ1 mouse monoclonal antibody,clone OTI2D2 100 ul
$447.00
RC205802 PATZ1 (Myc-DDK-tagged)-Human POZ (BTB) and AT hook containing zinc finger 1 (PATZ1), transcript variant 4
10 ug
$500.00

Other products for "PATZ1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PATZ1
Locus ID 23598
Components

GA108426G1, PATZ1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA108426G2, PATZ1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA108426G3, PATZ1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_014323, NM_032050, NM_032051, NM_032052
UniProt ID Q9HBE1
Synonyms dJ400N23; MAZR; PATZ; RIAZ; ZBTB19; ZNF278; ZSG
Summary The protein encoded by this gene contains an A-T hook DNA binding motif which usually binds to other DNA binding structures to play an important role in chromatin modeling and transcription regulation. Its Poz domain is thought to function as a site for protein-protein interaction and is required for transcriptional repression, and the zinc-fingers comprise the DNA binding domain. Since the encoded protein has typical features of a transcription factor, it is postulated to be a repressor of gene expression. In small round cell sarcoma, this gene is fused to EWS by a small inversion of 22q, then the hybrid is thought to be translocated (t(1;22)(p36.1;q12). The rearrangement of chromosome 22 involves intron 8 of EWS and exon 1 of this gene creating a chimeric sequence containing the transactivation domain of EWS fused to zinc finger domain of this protein. This is a distinct example of an intra-chromosomal rearrangement of chromosome 22. Four alternatively spliced transcript variants are described for this gene. provided by RefSeq, Jul 2008
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Documents
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Other Versions
SKU Description Size Price
KN405802 PATZ1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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