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Human LRRC8B activation kit by CRISPRa

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SKU
GA108351
LRRC8B CRISPRa kit - CRISPR gene activation of human leucine rich repeat containing 8 VRAC subunit B
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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100 ul
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RC205553 LRRC8B (Myc-DDK-tagged)-Human leucine rich repeat containing 8 family, member B (LRRC8B), transcript variant 1
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Other products for "LRRC8B"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol LRRC8B
Locus ID 23507
Components

GA108351G1, LRRC8B gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA108351G2, LRRC8B gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA108351G3, LRRC8B gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001134476, NM_015350, NM_001369817, NM_001369819
UniProt ID Q6P9F7
Synonyms TA-LRRP; TALRRP
Summary Non-essential component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes (PubMed:24790029, PubMed:26824658, PubMed:28193731). The VRAC channel conducts iodide better than chloride and can also conduct organic osmolytes like taurine. Channel activity requires LRRC8A plus at least one other family member (LRRC8B, LRRC8C, LRRC8D or LRRC8E); channel characteristics depend on the precise subunit composition (PubMed:24790029, PubMed:26824658, PubMed:28193731).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN405553 LRRC8B - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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