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Human RNF86 (TRIM2) activation kit by CRISPRa

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SKU
GA108217
TRIM2 CRISPRa kit - CRISPR gene activation of human tripartite motif containing 2
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA501606 TRIM2 mouse monoclonal antibody, clone OTI2B10 (formerly 2B10) 100 ul
$447.00
RC203947 TRIM2 (Myc-DDK-tagged)-Human tripartite motif containing 2 (TRIM2), transcript variant 1
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Other products for "TRIM2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol TRIM2
Locus ID 23321
Components

GA108217G1, RNF86 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA108217G2, RNF86 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA108217G3, RNF86 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001130067, NM_001302692, NM_001302693, NM_001302694, NM_015271, NM_001351054, NM_001351055, NM_001351056, NM_001351057
UniProt ID Q9C040
Synonyms CMT2R; RNF86
Summary The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic filaments. It plays a neuroprotective role and functions as an E3-ubiquitin ligase in proteasome-mediated degradation of target proteins. Mutations in this gene can cause early-onset axonal neuropathy. Alternative splicing results in multiple transcript variants. provided by RefSeq, Nov 2014
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Documents
Resources
Other Versions
SKU Description Size Price
KN403947 TRIM2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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