Human DENND5A activation kit by CRISPRa

SKU
GA108169
DENND5A CRISPRa kit - CRISPR gene activation of human DENN domain containing 5A
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol DENND5A
Locus ID 23258
Components

GA108169G1, DENND5A gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA108169G2, DENND5A gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA108169G3, DENND5A gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001243254, NM_015213, NM_001348748, NM_001348749, NM_001348750, NR_145966
UniProt ID Q6IQ26
Synonyms RAB6IP1
Summary This gene encodes a DENN-domain-containing protein that functions as a RAB-activating guanine nucleotide exchange factor (GEF). This protein catalyzes the conversion of GDP to GTP and thereby converts inactive GDP-bound Rab proteins into their active GTP-bound form. The encoded protein is recruited by RAB6 onto Golgi membranes and is therefore referred to as RAB6-interacting protein 1. This protein binds with RAB39 as well. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Mutations in this gene are associated with early infantile epileptic encephalopathy-49. provided by RefSeq, Feb 2017
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Documents
Resources
Other Versions
SKU Description Size Price
KN409850 DENND5A - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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