Human LARP4B activation kit by CRISPRa

SKU GA108105

LARP4B CRISPRa kit - CRISPR gene activation of human La ribonucleoprotein domain family member 4B

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: LARP4B
• Locus ID: 23185
• Components:

  GA108105G1, LARP4B gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA108105G2, LARP4B gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA108105G3, LARP4B gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_015155, NM_001351277
• UniProt ID: Q92615
• Synonyms: KIAA0217; LARP5
• Summary: This gene encodes a member of an evolutionarily conserved protein family implicated in RNA metabolism and translation. Members of this family are characterized by the presence of an La motif, which is often located adjacent to one or more RNA recognition motifs (RRM). Together, the two motifs constitute the functional region of the protein and enable its interaction with the RNA substrate. This protein family is divided into five sub-families: the genuine La proteins and four La-related protein (LARP) sub-families. The protein encoded by this gene belongs to LARP sub-family 4. It is a cytoplasmic protein that may play a stimulatory role in translation. [provided by RefSeq, Oct 2012]