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Human TAB2 activation kit by CRISPRa

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SKU
GA108051
TAB2 CRISPRa kit - CRISPR gene activation of human TGF-beta activated kinase 1 (MAP3K7) binding protein 2
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA330285 Rabbit Polyclonal Anti-MAP3K7IP2 Antibody
100 ul
$585.00
RC207721 TAB2 (Myc-DDK-tagged)-Human TGF-beta activated kinase 1/MAP3K7 binding protein 2 (TAB2)
10 ug
$952.00

Other products for "TAB2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol TAB2
Locus ID 23118
Components

GA108051G1, TAB2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA108051G2, TAB2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA108051G3, TAB2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001292034, NM_001292035, NM_015093, NM_145342, NR_125861, NM_001369506
UniProt ID Q9NYJ8
Synonyms CHTD2; MAP3K7IP2; TAB-2
Summary The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, and it thus serves as an adaptor that links MAP3K7 and TRAF6. This protein, along with TAB1 and MAP3K7, also participates in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappaB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts. Studies of the related mouse protein indicate that it functions to protect against liver damage caused by chemical stressors. Mutations in this gene cause congenital heart defects, multiple types, 2 (CHTD2). Alternative splicing results in multiple transcript variants. provided by RefSeq, May 2014
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Other Versions
SKU Description Size Price
KN407721 TAB2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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