Human KPI2 (LMTK2) activation kit by CRISPRa

SKU
GA107855
LMTK2 CRISPRa kit - CRISPR gene activation of human lemur tyrosine kinase 2
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol LMTK2
Locus ID 22853
Components

GA107855G1, KPI2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA107855G2, KPI2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA107855G3, KPI2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_014916
UniProt ID Q8IWU2
Synonyms AATYK2; BREK; cprk; hBREK; KPI-2; KPI2; LMR2; PPP1R100
Summary The protein encoded by this gene belongs to the protein kinase superfamily and the protein tyrosine kinase family. It contains N-terminal transmembrane helices and a long C-terminal cytoplasmic tail with serine/threonine/tyrosine kinase activity. This protein interacts with several other proteins, such as Inhibitor-2 (Inh2), protein phosphatase-1 (PP1C), p35, and myosin VI. It phosporylates other proteins, and is itself also phosporylated when interacting with cyclin-dependent kinase 5 (cdk5)/p35 complex. This protein involves in nerve growth factor (NGF)-TrkA signalling, and also plays a critical role in endosomal membrane trafficking. Mouse studies suggested an essential role of this protein in spermatogenesis. provided by RefSeq, Oct 2009
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Documents
Resources
Other Versions
SKU Description Size Price
KN416097 LMTK2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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