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Human HP1 gamma (CBX3) activation kit by CRISPRa

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SKU
GA107802
CBX3 CRISPRa kit - CRISPR gene activation of human chromobox 3
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA374324 HP1 gamma/CBX3 Rabbit polyclonal Antibody
100 ul
$475.00
RC201478 CBX3 (Myc-DDK-tagged)-Human chromobox homolog 3 (CBX3), transcript variant 1
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Other products for "CBX3"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CBX3
Locus ID 11335
Components

GA107802G1, HP1 gamma gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA107802G2, HP1 gamma gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA107802G3, HP1 gamma gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_007276, NM_016587
UniProt ID Q13185
Synonyms HECH; HP1-GAMMA; HP1Hs-gamma
Summary At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.provided by RefSeq, Mar 2011
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Documents
Resources
Other Versions
SKU Description Size Price
KN401478 CBX3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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