Human POLG2 activation kit by CRISPRa

SKU
GA107738
POLG2 CRISPRa kit - CRISPR gene activation of human DNA polymerase gamma 2, accessory subunit
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol POLG2
Locus ID 11232
Components

GA107738G1, POLG2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA107738G2, POLG2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA107738G3, POLG2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_007215
UniProt ID Q9UHN1
Synonyms HP55; MTPOLB; PEOA4; POLB; POLG-BETA; POLGB
Summary This gene encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The encoded protein forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions.provided by RefSeq, Sep 2009
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Documents
Resources
Other Versions
SKU Description Size Price
KN403462 POLG2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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