Human IRAKM (IRAK3) activation kit by CRISPRa

SKU GA107723

IRAK3 CRISPRa kit - CRISPR gene activation of human interleukin 1 receptor associated kinase 3

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: IRAK3
• Locus ID: 11213
• Components:

  GA107723G1, IRAKM gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA107723G2, IRAKM gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA107723G3, IRAKM gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001142523, NM_007199
• UniProt ID: Q9Y616
• Synonyms: ASRT5; IRAKM
• Summary: This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]