Human ADAMTS6 activation kit by CRISPRa
Specifications
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | ADAMTS6 |
| Locus ID | 11174 |
| Components |
GA107696G1, ADAMTS6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107696G2, ADAMTS6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107696G3, ADAMTS6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_014273, NM_197941, NR_135689 |
| UniProt ID | Q9UKP5 |
| Synonyms | ADAM-TS6; ADAM metallopeptidase with thrombospondin type 1 motif, 6; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 6; a disintegrin and metalloproteinase with thrombospondin motifs 6 |
| Summary | This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. Expression of this gene may be regulated by the cytokine TNF-alpha. provided by RefSeq, Mar 2016 |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| KN420803 | ADAMTS6 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit |
$1,657.00
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Citations
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