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Human LECT1 (CNMD) activation kit by CRISPRa

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SKU
GA107600
CNMD CRISPRa kit - CRISPR gene activation of human chondromodulin
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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100 ul
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RC213301 LECT1 (Myc-DDK-tagged)-Human leukocyte cell derived chemotaxin 1 (LECT1), transcript variant 1
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Other products for "CNMD"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CNMD
Locus ID 11061
Components

GA107600G1, LECT1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA107600G2, LECT1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA107600G3, LECT1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001011705, NM_007015
UniProt ID O75829
Synonyms BRICD3; CHM-I; CHM1; MYETS1
Summary This gene encodes a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The N-terminus of the precursor protein shares characteristics with other surfactant proteins and is sometimes called chondrosurfactant protein although no biological activity has yet been defined for it. The C-terminus of the precursor protein contains a 25 kDa mature protein called leukocyte cell-derived chemotaxin-1 or chondromodulin-1. The mature protein promotes chondrocyte growth and inhibits angiogenesis. This gene is expressed in the avascular zone of prehypertrophic cartilage and its expression decreases during chondrocyte hypertrophy and vascular invasion. The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone. It may be involved also in the broad control of tissue vascularization during development. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN406635 CNMD - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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