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Human SEC61B activation kit by CRISPRa

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SKU
GA107515
SEC61B CRISPRa kit - CRISPR gene activation of human SEC61 translocon beta subunit
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA381334 SEC61B Rabbit polyclonal Antibody
100 ul
$475.00
RC200247 SEC61B (Myc-DDK-tagged)-Human Sec61 beta subunit (SEC61B)
10 ug
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Other products for "SEC61B"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol SEC61B
Locus ID 10952
Components

GA107515G1, SEC61B gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA107515G2, SEC61B gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA107515G3, SEC61B gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_006808
UniProt ID P60468
Synonyms OTTHUMP00000021784; protein translocation complex beta; protein transport protein SEC61 beta subunit; Sec61 beta subunit; Sec61 complex, beta subunit
Summary The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the beta-subunit protein. The Sec61 subunits are also observed in the post-ER compartment, suggesting that these proteins can escape the ER and recycle back. There is evidence for multiple polyadenylated sites for this transcript. provided by RefSeq, Jul 2008
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Documents
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Other Versions
SKU Description Size Price
KN400247 SEC61B - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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