Human Peroxiredoxin 3 (PRDX3) activation kit by CRISPRa

SKU
GA107499
PRDX3 CRISPRa kit - CRISPR gene activation of human peroxiredoxin 3
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PRDX3
Locus ID 10935
Components

GA107499G1, Peroxiredoxin 3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA107499G2, Peroxiredoxin 3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA107499G3, Peroxiredoxin 3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001302272, NM_006793, NM_014098, NR_126102, NR_126103, NR_126105, NR_126106
UniProt ID P30048
Synonyms AOP-1; AOP1; HBC189; MER5; PRO1748; prx-III; SP-22
Summary This gene encodes a mitochondrial protein with antioxidant function. The protein is similar to the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase, and it can rescue bacterial resistance to alkylhydroperoxide in E. coli that lack the C22 subunit. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologs suggest that these genes consist of a family that is responsible for the regulation of cellular proliferation, differentiation and antioxidant functions. This family member can protect cells from oxidative stress, and it can promote cell survival in prostate cancer. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1, 3, 13 and 22. provided by RefSeq, Oct 2014
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Documents
Resources
Other Versions
SKU Description Size Price
KN405080 PRDX3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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