Human CLPX activation kit by CRISPRa

SKU
GA107426
CLPX CRISPRa kit - CRISPR gene activation of human caseinolytic mitochondrial matrix peptidase chaperone subunit
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CLPX
Locus ID 10845
Components

GA107426G1, CLPX gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA107426G2, CLPX gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA107426G3, CLPX gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_006660, NR_133680
UniProt ID O76031
Synonyms ClpX caseinolytic peptidase X homolog (E. coli); ClpX caseinolytic protease X homolog; energy-dependent regulator of proteolysis
Summary The protein encoded by this gene is part of a protease found in mitochondria. This protease is ATP-dependent and targets specific proteins for degradation. The protease consists of two heptameric rings of the CLPP catalytic subunit sandwiched between two hexameric rings of the chaperone subunit encoded by this gene. Targeted proteins are unwound by this protein and then passed on to the CLPP subunit for degradation. Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene. provided by RefSeq, Nov 2015
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Documents
Resources
Other Versions
SKU Description Size Price
KN415555 CLPX - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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