Human FRS2 activation kit by CRISPRa

SKU
GA107417
FRS2 CRISPRa kit - CRISPR gene activation of human fibroblast growth factor receptor substrate 2
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol FRS2
Locus ID 10818
Components

GA107417G1, FRS2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA107417G2, FRS2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA107417G3, FRS2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001042555, NM_001278351, NM_001278353, NM_001278354, NM_001278355, NM_001278356, NM_001278357, NM_006654
UniProt ID Q8WU20
Synonyms FRS1A; FRS2A; FRS2alpha; SNT; SNT-1; SNT1
Summary Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
KN405842 FRS2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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