Human Lefty (LEFTY1) activation kit by CRISPRa

SKU
GA107288
LEFTY1 CRISPRa kit - CRISPR gene activation of human left-right determination factor 1
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol LEFTY1
Locus ID 10637
Components

GA107288G1, Lefty gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA107288G2, Lefty gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA107288G3, Lefty gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_020997
UniProt ID O75610
Synonyms LEFTB; LEFTYB
Summary This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which plays a role in left-right asymmetry determination of organ systems during development. This gene is closely linked to both a related family member and a related pseudogene. provided by RefSeq, Aug 2016
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Other Versions
SKU Description Size Price
KN406459 LEFTY1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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