Human SH2B2 activation kit by CRISPRa

SKU
GA107257
SH2B2 CRISPRa kit - CRISPR gene activation of human SH2B adaptor protein 2
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol SH2B2
Locus ID 10603
Components

GA107257G1, SH2B2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA107257G2, SH2B2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA107257G3, SH2B2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_020979, NM_001359228, NM_001359229, NM_001359230, NM_001359231
UniProt ID O14492
Synonyms APS
Summary The protein encoded by this gene is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt's lymphoma cell lines, it is tyrosine-phosphorylated in response to B cell receptor stimulation. Because it binds Shc independent of stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to the Shc/Grb2 pathway. provided by RefSeq, Jun 2009
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Documents
Resources
Other Versions
SKU Description Size Price
KN416814 SH2B2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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