OriGene Logo

Customer Login

Checkout as a new customer

Creating an account has many benefits:

  • See order and shipping status
  • Track order history
  • Check out faster
Create an Account

Human TXNRD2 activation kit by CRISPRa

Be the first to review this product
SKU
GA107244
TXNRD2 CRISPRa kit - CRISPR gene activation of human thioredoxin reductase 2
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA311671 Rabbit polyclonal anti-TRXR2 antibody
100 ul
$380.00
RC237559L3V Lenti ORF particles, TXNRD2 (myc-DDK-tagged) - Human thioredoxin reductase 2 (TXNRD2), transcript variant 2, 200ul, >10^7 TU/mL
200 ul
$1,053.00

Other products for "TXNRD2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol TXNRD2
Locus ID 10587
Components

GA107244G1, TXNRD2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA107244G2, TXNRD2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA107244G3, TXNRD2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001282512, NM_006440, NM_145747, NM_145748, NM_001352300, NM_001352301, NM_001352302, NM_001352303, NR_147957
UniProt ID Q9NNW7
Synonyms SELZ; TR; TR-BETA; TR3; TRXR2
Summary The protein encoded by this gene belongs to the pyridine nucleotide-disulfide oxidoreductase family, and is a member of the thioredoxin (Trx) system. Three thioredoxin reductase (TrxR) isozymes are found in mammals. TrxRs are selenocysteine-containing flavoenzymes, which reduce thioredoxins, as well as other substrates, and play a key role in redox homoeostasis. This gene encodes a mitochondrial form important for scavenging reactive oxygen species in mitochondria. It functions as a homodimer containing FAD, and selenocysteine (Sec) at the active site. Sec is encoded by UGA codon that normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, the Sec insertion sequence (SECIS) element, which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternatively spliced transcript variants encoding different isoforms, including a few localized in the cytosol and some lacking the C-terminal Sec residue, have been found for this gene. provided by RefSeq, Jun 2017
Reviews
Write Review
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources
Other Versions
SKU Description Size Price
KN420848 TXNRD2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products