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Human SPTLC1 activation kit by CRISPRa

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SKU
GA107218
SPTLC1 CRISPRa kit - CRISPR gene activation of human serine palmitoyltransferase long chain base subunit 1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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RC222985 SPTLC1 (Myc-DDK-tagged)-Human serine palmitoyltransferase, long chain base subunit 1 (SPTLC1), transcript variant 1
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Other products for "SPTLC1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol SPTLC1
Locus ID 10558
Components

GA107218G1, SPTLC1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA107218G2, SPTLC1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA107218G3, SPTLC1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001281303, NM_006415, NM_178324, NM_001368273, NM_001368272
UniProt ID O15269
Synonyms HSAN1; HSN1; LBC1; LCB1; SPT1; SPTI
Summary This gene encodes a member of the class-II pyridoxal-phosphate-dependent aminotransferase family. The encoded protein is the long chain base subunit 1 of serine palmitoyltransferase. Serine palmitoyltransferase converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate and is the key enzyme in sphingolipid biosynthesis. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. Pseudogenes of this gene have been defined on chromosomes 1, 6, 10, and 13. provided by RefSeq, Jul 2013
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Documents
Resources
Other Versions
SKU Description Size Price
KN416310 SPTLC1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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