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Human Semaphorin 3c (SEMA3C) activation kit by CRISPRa

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SKU
GA107179
SEMA3C CRISPRa kit - CRISPR gene activation of human semaphorin 3C
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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100 ul
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RC205269 SEMA3C (Myc-DDK-tagged)-Human sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C (SEMA3C)
10 ug
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Other products for "SEMA3C"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol SEMA3C
Locus ID 10512
Components

GA107179G1, Semaphorin 3c gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA107179G2, Semaphorin 3c gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA107179G3, Semaphorin 3c gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_006379, NM_001350120, NM_001350121
UniProt ID Q99985
Synonyms SEMAE; SemE
Summary This gene encodes a secreted glycoprotein that belongs to the semaphorin class 3 family of neuronal guidance cues. The encoded protein contains an N-terminal sema domain, integrin and immunoglobulin-like domains, and a C-terminal basic domain. Homodimerization and proteolytic cleavage of the C-terminal propeptide are necessary for the function of the encoded protein. It binds a neuropilin co-receptor before forming a heterotrimeric complex with an associated plexin. An increase in the expression of this gene correlates with an increase in cancer cell invasion and adhesion. Naturally occurring mutations in this gene are associated with Hirschsprung disease. provided by RefSeq, May 2017
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Documents
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Other Versions
SKU Description Size Price
KN405269 SEMA3C - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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