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Human Bim (BCL2L11) activation kit by CRISPRa

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SKU
GA106786
BCL2L11 CRISPRa kit - CRISPR gene activation of human BCL2 like 11
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA812441 BCL2L11 mouse monoclonal antibody,clone OTI2H5 100 ul
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RC207559 BCL2L11 (Myc-DDK-tagged)-Human BCL2-like 11 (apoptosis facilitator) (BCL2L11), transcript variant 1
10 ug
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Other products for "BCL2L11"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol BCL2L11
Locus ID 10018
Components

GA106786G1, Bim gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA106786G2, Bim gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA106786G3, Bim gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001204106, NM_001204107, NM_001204108, NM_001204109, NM_001204110, NM_001204111, NM_001204112, NM_001204113, NM_006538, NM_138621, NM_138622, NM_138623, NM_138624, NM_138625, NM_138626, NM_138627, NM_207002, NM_207003
UniProt ID O43521
Synonyms BAM; BIM; BOD
Summary The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified. provided by RefSeq, Jun 2013
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Documents
Resources
Other Versions
SKU Description Size Price
KN407559 BCL2L11 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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