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Human TL1A (TNFSF15) activation kit by CRISPRa

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SKU
GA106744
TNFSF15 CRISPRa kit - CRISPR gene activation of human TNF superfamily member 15
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC212177 TNFSF15 (Myc-DDK-tagged)-Human tumor necrosis factor (ligand) superfamily, member 15 (TNFSF15), transcript variant 1
10 ug
$300.00

Other products for "TNFSF15"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol TNFSF15
Locus ID 9966
Components

GA106744G1, TL1A gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA106744G2, TL1A gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA106744G3, TL1A gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001204344, NM_005118
UniProt ID O95150
Synonyms TL1; TL1A; TNLG1B; VEGI; VEGI192A
Summary The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Two transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Feb 2011
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Documents
Resources
Other Versions
SKU Description Size Price
KN412177 TNFSF15 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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