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Human KIF14 activation kit by CRISPRa

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SKU
GA106713
KIF14 CRISPRa kit - CRISPR gene activation of human kinesin family member 14
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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RC215782 KIF14 (Myc-DDK-tagged)-Human kinesin family member 14 (KIF14)
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Other products for "KIF14"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol KIF14
Locus ID 9928
Components

GA106713G1, KIF14 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA106713G2, KIF14 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA106713G3, KIF14 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001305792, NM_014875
UniProt ID Q15058
Synonyms MKS12
Summary This gene encodes a member of the kinesin-3 superfamily of microtubule motor proteins. These proteins are involved in numerous processes including vesicle transport, chromosome segregation, mitotic spindle formation, and cytokinesis. In human HeLa-S3 and 293T cells, this protein is localized to the cytoplasm during interphase, to the spindle poles and spindle microtubules during mitosis, and to the midbody during cytokinesis. An internal motor domain displays microtubule-dependent ATPase activity, consistent with its function as a microtubule motor protein. Knockdown of this gene results in failed cytokinesis with endoreplication, which results in multinucleated cells. This gene has been identified as a likely oncogene in breast, lung and ovarian cancers, as well as retinoblastomas and gliomas. Alternative splicing results in multiple transcript variants. provided by RefSeq, Mar 2015
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Documents
Resources
Other Versions
SKU Description Size Price
KN415782 KIF14 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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