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Human DRIP130 (MED23) activation kit by CRISPRa

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SKU
GA106300
MED23 CRISPRa kit - CRISPR gene activation of human mediator complex subunit 23
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA314909 Rabbit polyclonal anti-MED23 antibody
100 ul
$380.00
RC219530 MED23 (Myc-DDK-tagged)-Human mediator complex subunit 23 (MED23), transcript variant 2
10 ug
$589.00 $1,168.00

Other products for "MED23"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol MED23
Locus ID 9439
Components

GA106300G1, DRIP130 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA106300G2, DRIP130 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA106300G3, DRIP130 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001270521, NM_001270522, NM_004830, NM_015979
UniProt ID Q9ULK4
Synonyms ARC130; CRSP3; CRSP130; CRSP133; DRIP130; MRT18; SUR-2; SUR2
Summary The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein also acts as a metastasis suppressor. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. provided by RefSeq, Jul 2012
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Documents
Resources
Other Versions
SKU Description Size Price
KN419530 MED23 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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