Human Klotho (KL) activation kit by CRISPRa

SKU
GA106246
KL CRISPRa kit - CRISPR gene activation of human klotho
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol KL
Locus ID 9365
Components

GA106246G1, Klotho gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA106246G2, Klotho gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA106246G3, Klotho gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_004795, NM_153683
UniProt ID Q9UEF7
Synonyms klotho; OTTHUMP00000018796
Summary This gene encodes a type-I membrane protein that is related to beta-glucosidases. Reduced production of this protein has been observed in patients with chronic renal failure (CRF), and this may be one of the factors underlying the degenerative processes (e.g., arteriosclerosis, osteoporosis, and skin atrophy) seen in CRF. Also, mutations within this protein have been associated with ageing and bone loss. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN424132 KL - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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