Human P311 (NREP) activation kit by CRISPRa

SKU GA106207

NREP CRISPRa kit - CRISPR gene activation of human neuronal regeneration related protein

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: NREP
• Locus ID: 9315
• Components:

  GA106207G1, P311 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA106207G2, P311 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA106207G3, P311 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001142474, NM_001142475, NM_001142476, NM_001142477, NM_001142478, NM_001142479, NM_001142480, NM_001142481, NM_001142482, NM_001142483, NM_004772
• UniProt ID: Q16612
• Synonyms: C5orf13; D4S114; P311; PRO1873; PTZ17; SEZ17
• Summary: May have roles in neural function. Ectopic expression augments motility of gliomas. Promotes also axonal regeneration (By similarity). May also have functions in cellular differentiation (By similarity). Induces differentiation of fibroblast into myofibroblast and myofibroblast ameboid migration. Increases retinoic-acid regulation of lipid-droplet biogenesis (By similarity). Down-regulates the expression of TGFB1 and TGFB2 but not of TGFB3 (By similarity). May play a role in the regulation of alveolar generation.[UniProtKB/Swiss-Prot Function]