Human SOCS6 activation kit by CRISPRa

SKU
GA106200
SOCS6 CRISPRa kit - CRISPR gene activation of human suppressor of cytokine signaling 6
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol SOCS6
Locus ID 9306
Components

GA106200G1, SOCS6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA106200G2, SOCS6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA106200G3, SOCS6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_004232
UniProt ID O14544
Synonyms CIS-4; CIS4; HSPC060; SOCS-4; SOCS-6; SOCS4; SSI4; STAI4; STATI4
Summary The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN402224 SOCS6 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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