Human EMAP II (AIMP1) activation kit by CRISPRa

SKU
GA106173
AIMP1 CRISPRa kit - CRISPR gene activation of human aminoacyl tRNA synthetase complex interacting multifunctional protein 1
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol AIMP1
Locus ID 9255
Components

GA106173G1, EMAP II gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA106173G2, EMAP II gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA106173G3, EMAP II gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001142415, NM_001142416, NM_004757
UniProt ID Q12904
Synonyms EMAP2; EMAPII; HLD3; p43; SCYE1
Summary The protein encoded by this gene is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene has been identified on chromosome 20. provided by RefSeq, Dec 2008
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Documents
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Other Versions
SKU Description Size Price
KN404150 AIMP1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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