Human MCT2 (SLC16A7) activation kit by CRISPRa

SKU GA106129

SLC16A7 CRISPRa kit - CRISPR gene activation of human solute carrier family 16 member 7

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: SLC16A7
• Locus ID: 9194
• Components:

  GA106129G1, MCT2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA106129G2, MCT2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA106129G3, MCT2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001270622, NM_001270623, NM_004731, NR_073055, NR_073056
• UniProt ID: O60669
• Synonyms: MCT2
• Summary: This gene is a member of the monocarboxylate transporter family. Members in this family transport metabolites, such as lactate, pyruvate, and ketone bodies. The protein encoded by this gene catalyzes the proton-linked transport of monocarboxylates and has the highest affinity for pyruvate. This protein has been reported to be more highly expressed in prostate and colorectal cancer specimens when compared to control specimens. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]